Susumu Seino Selected Research

Glutamic Acid (Glutamate)

10/2014

Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.

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Susumu Seino Research Topics

Disease

22	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2004
10	Insulin Resistance 01/2020 - 12/2003
9	Ischemia 04/2007 - 02/2002
8	Glucose Intolerance 01/2019 - 12/2004
7	Hyperglycemia 12/2020 - 12/2004
7	Diabetes Mellitus 11/2020 - 08/2011
6	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019 - 08/2002
6	Hypoxia (Hypoxemia) 06/2008 - 09/2003
5	Obesity 03/2019 - 01/2012
5	Heart Failure 04/2012 - 08/2006
4	Hypoglycemia (Reactive Hypoglycemia) 01/2011 - 08/2004
3	Hypertension (High Blood Pressure) 04/2012 - 08/2006
3	Hypertrophy 03/2011 - 12/2006
3	Reperfusion Injury 09/2003 - 02/2002
2	Neoplasms (Cancer) 11/2020 - 02/2010
2	Cardiomyopathies (Cardiomyopathy) 01/2018 - 10/2008
2	Hyperinsulinism (Hyperinsulinemia) 03/2015 - 01/2011
2	Myocardial Ischemia (Ischemic Heart Diseases) 10/2008 - 01/2005
2	Channelopathies 02/2007 - 08/2006
2	Cardiac Arrhythmias (Arrythmia) 12/2004 - 10/2002
2	Seizures (Absence Seizure) 12/2004 - 09/2003
1	Wolfram Syndrome (Syndrome, Wolfram) 10/2018
1	Metabolic Diseases (Metabolic Disease) 01/2018
1	Prediabetic State (Prediabetes) 01/2015
1	Malnutrition (Nutritional Deficiencies) 09/2013
1	Diabetic Retinopathy (Retinopathy, Diabetic) 04/2013
1	Parkinson Disease (Parkinson's Disease) 09/2012
1	Myositis Ossificans (Fibrodysplasia Ossificans Progressiva) 07/2012
1	Heterotopic Ossification (Ectopic Ossification) 07/2012
1	Acromegaly 04/2012
1	Atherosclerosis 04/2012
1	Body Weight (Weight, Body) 05/2011

Drug/Important Bio-Agent (IBA)

25	Adenosine Triphosphate (ATP)IBA 09/2012 - 02/2002
18	Insulin (Novolin)FDA Link 01/2020 - 03/2003
15	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 12/2003
10	IncretinsIBA 01/2022 - 05/2011
8	Proteins (Proteins, Gene)FDA Link 01/2020 - 06/2003
8	Glucagon (Glukagon)FDA Link 01/2019 - 12/2004
7	KATP ChannelsIBA 01/2018 - 12/2003
4	PotassiumIBA 07/2015 - 02/2003
3	Liraglutide FDA Link 10/2018 - 01/2015
3	Glucagon-Like Peptide 1 (GLP 1)IBA 10/2018 - 05/2011
3	Insulin-Like Growth Factor I (IGF-1)IBA 09/2013 - 03/2011
3	Growth Hormone (Somatotropin)IBA 09/2013 - 01/2011
2	ArsenicIBA 01/2019 - 01/2018
2	Endocrine DisruptorsIBA 01/2019 - 01/2018
2	Glucagon-Like Peptide-1 ReceptorIBA 10/2018 - 01/2017
2	Insulin SecretagoguesIBA 01/2017 - 01/2016
2	Hormones (Hormone)IBA 01/2017 - 05/2011
2	Blood Glucose (Blood Sugar)IBA 01/2016 - 03/2003
2	C-PeptideIBA 09/2015 - 10/2013
2	Leptin ReceptorsIBA 01/2015 - 01/2013
2	ProteomeIBA 01/2012 - 03/2009
2	TOR Serine-Threonine KinasesIBA 03/2011 - 01/2011
2	Nonsense Codon (Nonsense Mutation)IBA 03/2008 - 08/2002
2	CalciumIBA 12/2006 - 08/2006
2	ElementsIBA 11/2006 - 08/2006
1	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 01/2020
1	Amino Acids FDA Link 01/2020
1	Leukotriene B4IBA 01/2020
1	CarbohydratesIBA 03/2019
1	Arginine (L-Arginine)FDA Link 01/2019
1	SodiumIBA 01/2018
1	Amino Acid Transport Systems (Amino Acid Transporter)IBA 01/2018
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2018
1	Drinking WaterIBA 01/2018
1	Glutamine (L-Glutamine)FDA Link 01/2018
1	LinagliptinIBA 01/2017
1	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2017
1	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 01/2017
1	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2017
1	DSC108IBA 01/2016
1	Insulin Glargine (Lantus)FDA Link 09/2015
1	insulin degludecIBA 09/2015
1	Secretin FDA Link 06/2015
1	AlloxanIBA 01/2015
1	Biomarkers (Surrogate Marker)IBA 01/2015
1	Tryptophan (L-Tryptophan)FDA Link 01/2015
1	Dihydrotachysterol (AT 10)IBA 01/2015
1	KynurenineIBA 01/2015
1	Glutamic Acid (Glutamate)FDA Link 10/2014
1	cyclopropapyrroloindoleIBA 10/2013
1	VildagliptinIBA 10/2012
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 09/2012
1	Phosphotransferases (Kinase)IBA 07/2012
1	Activin Receptors (Activin Receptor)IBA 07/2012
1	Thiobarbituric Acid Reactive SubstancesIBA 04/2012
1	ProgranulinsIBA 01/2012
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2012
1	Interleukin-6 (Interleukin 6)IBA 01/2012
1	AdipokinesIBA 01/2012

Therapy/Procedure

4	Therapeutics 09/2015 - 02/2007
2	Transplantation 08/2011 - 10/2008
1	Intravenous Administration 01/2019
1	Nutrition Therapy (Medical Nutrition Therapy) 03/2016
1	Oral Administration 01/2016
1	Injections 09/2015
1	Cardiopulmonary Resuscitation (CPR) 04/2013
1	Cell- and Tissue-Based Therapy (Cell Therapy) 03/2013
1	Glycemic Control 05/2011